Welcome @rupert
Don’t be afraid of @Al_kafir, its just he’s from Madchester.
I can’t answer defo about the Synology boxes/OS, but I do expect such devices to be supported if at all possible. I have an excito B3 that I was trying to build on (Debian/arm5) but have given up at least for now, but if the synology toolchain is up to date it should be feasible.
I have built and am running on a general purpose single board computer Odroid-U3 with Ubuntu 14.04.
VMs are definitely ok, though you might like to try a more lightweight Docker container. I’ve used this on Debian but not tried on Odroid as Docker don’t yet support 32 bit. There is a ready to use MaidSafe Docker container - see link.